gpx7 glutathione peroxidase 7 Reconstitution of (GPX7) expression suppresses Glutathione Peroxidase 7 (GPX7) Antibody

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The pentose phosphate pathway is sometimes described as a shunt, rather than a pathway, because when pentoses are not needed for biosynthetic reactions, the pentose phosphate intermediates are recycled back into the mainstream of glycolysis by conversion into Fru-6-P and glyceraldehyde-3-phosphate

To explore whether targeted intervention of Chac2 in neutrophils could alleviate the inflammatory comorbidity of periodontitis, we constructed AAV9 viruses targeting neutrophils to specifically knock down Chac2 (AAV-shCHAC2) and a control virus with no payload (AAV-NC), and administered them via intraosseous injection into a mouse model with periodontitis and diabetes comorbidity