l carnitine toxicity Supplementation in Chronic Hemodialysis Patients—A Literature Review The Role of l-Carnitine in
Description
Toxicology, 47(3): 295-305
Biomed Res Int 2015
ATP released from damaged cells and infiltrating immune cells can act as a danger signal and engages purinergic receptors on nociceptors and immune cells, thereby enhancing peripheral sensitization and inflammatory signaling [43,44]
ATP depletion further diminishes sarco/ER Ca-ATPase and plasma membrane Ca-ATPase pump activity, impairing Ca clearance from the cytosol and contributing to intracellular Ca overload
