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Copper complexes (e.g., CuET, CuHQ, CuCQ, CuPDTC, CuPT, and CuHK) are found to be able to inhibit a core component of the UPS machinery, such as 20S proteasome, 19S DUBs, and NPLOC4/NPL4 complex, and are proposed to be one class of metal-based anticancer drugs

Many clinics provide training for patients to self-inject at home, especially for long-term therapy

10.3389/fphar.2017.00992 91 LuS

M GSH-SN (0.0048), C GSH-SN (0.0013), M GSH-LH (0.0026), and C GSH-LH (0.0008) are slope and intercept values (from SN and LH regions, respectively) obtained from the linearly fitted calibration curve of GSH phantom experiments for SN and LH voxels, respectively (Supporting Information)