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Diseases associated with microbial translocation include alcoholism, inflammatory bowel disease (IBD), human immunodeficiency virus infection, Hepatitis B and C virus infection, and pancreatitis (Brenchley and Douek 2012)
So, if your vitamin B12 is not working properly because your folate metabolism isnt working properly this causes homocysteine imbalances which are considered a serious health problem for anyone, especially for those with MTHFR gene mutations
Morselli, L
Kopp MA, Liebscher T, Niedeggen A, Laufer S, Brommer B, Jungehulsing GJ, et al
