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This deficit correlates with disease activity, suggesting that reduced thymosin alpha-1 may contribute to the immune dysregulation seen in SLE

A clinical study published in the Journal of Cosmetic Dermatology and funded by the Avocado Nutrition Center examined the relationship between avocado consumption and skin aging in 39 women aged 27-73 years

They found that ethanol-induced gastric ulcer was associated with Nrf2 downregulation and, at the same time, caused the upregulation of NOX-1, 2, and 4 and high-mobility group box-1 (HMGB1), a nucleoprotein that mediates inflammatory functions

They can be directly involved in scavenging ROS to protect organisms from oxidative damage and participate in several physiological processes (Table 1)