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this kind of GPXs are shown to be reduced by redoxins, namely, thioredoxins or related proteins with a CXXC motif in plants, yeast, insects and protists 15,17

Topical ocular instillation of acetylcholine to the intact eye causes no discernible response as cholinesterase destroys the molecule more rapidly than it can penetrate the cornea

Strikingly, older mice treated with the peptide can run for twice as long as their untreated counterparts