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McAuliffeJVogelLRobertsAFahleGFischerSShiehWJet al

Chao et al

Taken together, our results provide a mechanistic rationale for KEAP1NRF2-targeted interventions in MIBC and highlight how abrogating tumor antioxidant defenses and cell plasticity can synergize with conventional chemotherapy to yield superior anticancer effects

It is formed by reverse splicing of pre-mRNA, and some circRNAs are abundant and evolutionarily conserved (Misir et al., 2022)
