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Description
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Cisplatin-mediated impairment of mitochondrial DNA metabolism inversely correlates with glutathione levels
doi: 10.1016/j.peptides.2006.07.014
Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response
