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Common side effects may include: Dizziness Pain, swelling, or itching at the injection site Diarrhea Nausea Skin rash or acne-like skin Unwell or feeling of weakness Serious side effects may include: Difficulty breathing Swelling of the face, lips, or tongue Irregular heartbeats or palpitations Swelling or pain in the limbs due to blood clots Severe dizziness or weakness This list does not cover all potential side effects, and others may occur

Coming off Category 2 is not FDA approval, and the PCAC review concerns pharmacy compounding, not research-grade material

The REDEFINE program is the first group of clinical trials to study semaglutide and cagrilintide alone and in combination

PMID 38665151