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Human 3-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

Nature 480, 109112 (2011)

Mirtazapine, the first noradrenergic and specific serotonergic antidepressant (NaSSA) with presynaptic antagonistic, 5-HT receptor stimulating, and 5-HT2/5-HT3 receptor-blocking properties, has been linked in a number of case reports to RLS

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