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Description
Nichols, D.A
A structure-based design approach was undertaken to develop IACS-16898 (Fig

Parenteral administration of minute amounts of endotoxins to humans elicits an inflammatory reaction typical of SIRS (fever or hypothermia, tachycardia, hyperpnea, leukocytosis, and hypotension), whereas larger amounts of administered endotoxins typically produce sepsis and shock [66, 67]
Shak, S., Capon, D
