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According to studies conducted by Jiang Ji and others, ionizing radiation affects primary keloid fibroblasts (KFb), causing damage to their DNA [90]

J Control Release (2021) 331:48090

The gut microbiota carry out many functions which can contribute to health homeostasis or disease, including metabolism of dietary components (eg, fiber, amino acids) and endogenous compounds (eg, bile acids, hormones), and biosynthesis of lipopolysaccharide (LPS), a cell wall component of gram-negative bacteria which triggers inflammation

Determining biochemical pattern of liver injury (hepatocellular, cholestatic, mixed) by calculating the R factor, while systematically ruling out alternative etiologies of liver disease (Figure 3)