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Symptoms of too much vitamin B12 Dr Thornber said one of the signs of too much vitamin B12 is urine discolouration

Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (, )

These compounds combined enhance liver function and increase the flow of fats and bile from the liver and gallbladder