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Description
Devaney J
21 LuJ-CHuangY-FLN-Q
Additional contributing factors include increased expression of insulin-like growth factor 1 (IGF1) receptors, IGF1-binding protein (which protects IGF1 from proteolysis) in Purkinje cells [8], as well as upregulated mRNA expression of GLUT1 and GLUT3 [80]
The critical period for use of SAMe or related agents has been proposed to be as early as possible, thus enhancing therapeutic effects and/or potentially preventing the illness from manifesting in the first place
