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B12 vitamins produce melatonin, which controls our sleep and wake cycles

[DOI] [PMC free article] [PubMed] [Google Scholar] 244.Gauthier MS, Miyoshi H, Souza SC, Cacicedo JM, Saha AK, Greenberg AS, et al

Some patients notice improved energy or mental clarity within 2448 hours, whilst others experience no immediate change, particularly if deficiency is severe

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