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They also found that empagliflozin increases the gene expression levels of the major lipases ( Lipe and Pnpla2 ) in gWAT, providing a potential mechanistic explanation of the lipidome-modifying role of empagliflozin in adipose tissue 79

Andermann, M

Based on these data, it is reasonable to surmise that disrupting mitochondrial function, either directly by targeting OXPHOS, or by otherwise reducing mitochondrial performance, is connected with the formation of melanotic nodules, and hence the immune activation of hemocytes

[DOI] [PubMed] [Google Scholar] 33.Kintarak S., Whawell S.A., Speight P.M., Packer S., Nair S.P