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Reduced lysosomal proteolytic and cathepsin B activity were observed in tumor cells from homoarginine-treated mice compared with their activity in tumor cells from control mice (Supplementary Fig

doi: 10.1634/theoncologist.12-5-594

This reaction is catalyzed by two mitochondrial enzymes: 4-aminobutyrate-2-oxoglutarate transaminase (also known as GABA-T or -alanine-2-oxoglutarate transaminase) and alanine-glyoxylate transaminase (also called AGXT2 or -alanine-pyruvate transaminase) [44,45,46]

doi: 10.1146/annurev.me.34.020183.001251
