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CLINICAL AND METABOLIC IMPACT OF GLUTAMINE SUPPLEMENTATION IN DISEASE STATES Cytoprotective Effects Numerous studies have demonstrated that exogenous glutamine supplementation exerts effects that can be considered cytoprotective and include protein anabolic effects and improved nitrogen balance after major surgery (2, 5, 7, 8, 13, 48, 49, 50, 51, 52)

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Data from the mouse study indicated that two weeks of supplementation with glutathione prevented the decrease in intramuscular pH, which typically occurs as lactic acid builds up