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The LRRK2 induced DA toxicity and degeneration could be abrogated by WT PINK1 (but not PINK1 mutations) and early treatment with -MT was able to reverse the pathologies in human neurons and TG Drosophila models with pathogenic LRRK2 mutations
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doi: 10.1038/s41467-023-37849-3 173 WuY.JhaR.LiA.LiuH.ZhangZ.ZhangC.et al
