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Treatment usually involves a twice-daily oral dosage, which may be challenging for some owners to maintain

Interventions like fetal microbiota transplantation, probiotics, and prebiotics can improve microbial balance, but more clinical research is needed

The disease has numerous consequences, including anemia causing fatigue, bone loss resulting in weakening of the bones, bone fractures, and pain, kidney damage sometimes resulting in the need for dialysis, high calcium levels, altered immunity resulting in infections, and nerve damage which can cause numbness, tingling, or even pain and loss of strength

Hence, the purpose of this review is to discuss the structure and life cycle of HSV, progress in the development of new therapies, emerging therapeutics under clinical development and finally related recent patents involving the treatment of herpes simplex virus infections