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Continuous oxidative stress can lead to chronic inflammation, intense cytokine release and a cytokine storm as seen in SARS-CoV-2 infection in COVID-19 disease, and the viral infection enhances oxidative stress creating a fatal vicious circle between oxidative stress and cytokine storm during COVID-19 infection (Delgado-Roche and Mesta, 2020

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Transient Chest Tightness and Flushing: Why it Happens One common side effect observed during NAD IV infusions is transient chest tightness or a feeling of warmth, often accompanied by flushing