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In women with episodic migraines ( n = 92), ALA (300 mg twice daily) for 12 weeks significantly reduced migraine severity and frequency, and reduced serum lactate and vascular cell adhesion molecule-1, suggesting improvement in mitochondrial and endothelial function, respectively

These metrics provide the basis for diagnosing dyslipidemia, assessing cardiovascular risk (ASCVD) and monitoring a patients response to lifestyle or pharmacologic therapy

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