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Antioxid Redox Signal (2016) 24:54855

In patients with autoimmune hypothyroidism, thyroid dysfunction might be induced by cytokine-mediated apoptosis of thyroid epithelial cells and infiltrating T lymphocytes may not directly be involved in thyrocyte cell death during Hashimoto' s thyroiditis

Anterior and apical surfaces are covered by the anterior fibromuscular stroma, which is thinner than the fibrous capsule covering the posterior gland [10]

As a result, drugs in this class are FDA recommended for use only in RA patients who have failed to respond to TNF bDMARDs (Cohen 2023)
