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The inflammatory response produced by articular and periarticular tissue, one of the major factors accelerating the process of OA progression, is predominantly the skew of the macrophage polarization towards the M1 phenotype (Mahon et al., 2020)

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At least 20 of them code for functional peptides due to the fact that typical conserved -defensin characteristics are present in the primary sequences

These harmful chemicals lead to uneven skin tone, black patches, and early aging