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Ehninger D
Pirenoxine eye drops prevented hardening of the lens in rats and Pirenoxine improved the accommodation ability in human in a clinical study 7

Regarding NF-B inhibition, we postulate that HMB acts upstream of the NF-B complex, potentially by inhibiting the phosphorylation and degradation of the inhibitory protein IB, thereby preventing the nuclear translocation of the p65 subunit

The mechanism of action resulting in polycythemia may be primary or secondary
