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Description
Furthermore, ferroptosis, a regulated cell death pathway driven by iron-dependent lipid peroxidation, has recently emerged as a key mechanism in NAFLD progression [51,52]
FBW7 has been shown to regulate lipid peroxidation and enhance ferroptosis in pancreatic cancer and to inhibit stearoyal-CoA desaturase (SCD1) activity [57]
C.LeungV
Activated functions include CD8 + T lymphocyte proliferation, cellular immune responses, antigen expression, and cell death in tumor cell lines
