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Cartilage destruction is considered a hallmark of OA and is a result of increased production of catabolic effectors 32,33,34,35 and reduced matrix biosynthesis by chondrocytes 36

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Consequently, -synuclein, NLRP3 inflammasome, and IL-1 plasma could be biomarkers to monitor PD severity and progression

Our clinical guide to microneedling in Miami covers how SkinPen combined with exosomes and PDRN addresses both active acne damage and the post-inflammatory texture that Miami patients consistently deal with after breakout cycles
