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In human case reports involving serotonergic agents, symptoms progress from agitation and confusion to autonomic instability (tachycardia, blood pressure fluctuations), severe hyperthermia above 40C, and in extreme cases, rhabdomyolysis
doi: 10.1016/j.jmb.2005.07.017
doi:10.1097/yic.0000000000000276 Rissardo JP, Caprara ALF
