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Our work identifies a novel role for MYC in regulating the synthesis of glutathione, a major cellular antioxidant, via miR18a in primary tumors

Since mutant NRAS is known to drive glutamine dependency in melanoma 17 , we investigated the effect of glutamine supplementation in HMCB xenografts, which express wild-type BRAF and mutant NRAS, and found that increased glutamine intake hindered growth in these tumours compared to the control diet group (Supplementary Fig

Clearing method for 3-dimensional immunofluorescence of osteoarthritic subchondral human bone reveals peripheral cholinergic nerves