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Previous reports of molecular glues that first bind to a target and then cooperatively engage an E3 ligase have largely relied on serendipity or target-agnostic screens 18,19,20,21,22,82,83,84

Abstract The proinflammatory (N1) polarization of bone marrow (BM) neutrophils, driven by central immune remodeling in response to peripheral inflammation, plays a critical role in propagating localized inflammatory conditions, such as periodontitis, to systemic levels

However, prolonged exposure to high glucose for 2 days resulted in loss of contractility and cell swelling in MCs, while cells treated with SGLT2 inhibitors maintained contractile function

This enzyme is responsible for cysteine production