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Acetylation reduces SOD activity, resulting in higher mitochondrial O 2 levels, whereas irradiation, nutrient scarcity, and oxidative stress trigger SIRT3-mediated deacetylation of MnSOD to adequately enhance ROS scavenging within mitochondria to combat the emerging challenging conditions [16]

The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism
