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Cell migration assessment yielded similar results (Fig

The BSeC@MSNs-RGD with PEI coating was found to cross the BBB and disrupt brain cancer U87 VM channels and displayed inhibitory effects on the U87 tumor, therefore validating its anticancer efficacy in vivo
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Figure 2A clearly demonstrates the use of human artificial chromosome (HAC) vectors to develop Caco-2 cells co-expressing CYP3A4 and CYP450 reductase (CPR) (Takenaka et al., 2017)