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[DOI] [PubMed] [Google Scholar] 82.Brando F., Cadete-Leite A., Andrade J.P., Madeira M.D., Paula-Barbosa M.M

Decreased GABAergic neurotransmission due to excessive IL-17 levels in the spinal cord has been linked to CIPN caused by paclitaxel [171], and the inhibition of GABA reuptake with by NO-711, a selective GABA transporter isoform 1 (GAT-1) inhibitor [172], prevents the development of thermal hyperalgesia and allodynia in paclitaxel-treated mice

Caforio ALP, Rossi B, Risaliti R et al

Nutritional reset of virus-hijacked NRP1/neuro-cognitive impairment NRP1 is expressed in olfactory epithelium, astrocytes, and neuronal cells (which lack ACE2 expression) and serve as major CSR for SARSCoV2 infection of the central nervous system (CNS) 645,646
