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doi: 10.1084/jem.20211314
Protocol: Follistatin-344 cycles are kept short (10-30 days) due to the compound's potent effect on follicle-stimulating hormone (FSH), which can temporarily affect fertility in men
However, the applicability of the metabolomic analysis to assess the hepatotoxicity of drugs is complex and requires careful and systematic work, precise controls, wise data preprocessing and appropriate biological interpretation to make meaningful interpretations and/or predictions of drug hepatotoxicity
