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Two primary explanations for the destruction of SNpc dopaminergic neurons are the presence of Lewy pathology, which involves protein aggregates rich in fibrillary forms of alpha-synuclein, and mitochondrial malfunction
Glutathione may affect skin pigmentation by inhibiting tyrosinase activity during melanogenesis, either directly or indirectly
The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)
