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As with other antidepressants (notably including selective serotonin reuptake inhibitors), it may paradoxically increase the risk of suicide in those under the age of 25, at least in the first few weeks of treatment

Of relevance, NE inhibitors target also other serine proteinases released from neutrophils, namely cathepsin G and proteinase-3, that possibly contribute to emphysema development [3,16]

[DOI] [PubMed] [Google Scholar] (170).Fujioka T

Update on chemotherapy-induced peripheral neuropathy
