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39,40 Given the importance of serum phosphate levels, members of the Acute Liver Failure Study Group (commonly referred to as ASFLG) have included serum phosphate levels in their prognostic scoring system for mortality related to APAP hepatotoxicity

However, while HDAC6 inhibition reduced oxidative damage and preserved cartilage in mouse models and TBHP-treated chondrocytes, the spontaneous and slowly progressive nature of human osteoarthritis is not fully captured in these systems

10.1002/hep.28251 Hepatology

This possibility is supported by the findings of Ricciolini et al
