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Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )

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Amniotic tissue has been shown to exert an anti-inflammatory and anti-microbial effect in human tissue, thus injecting small amounts of this fluid was shown to significantly reduce foot pain, promote reduction of scar tissue, increase mobility and facilitate a quicker return to full activity post-injury and post-surgery

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