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Carnitine/acetylcarnitine also show great potential for improving complications in patients with liver disease because of their abilities to reduce ammonia toxicity [205207]
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Congruent with these latter findings, studies in rats utilizing a dependence model that involves chronic exposure to alcohol vapor have shown increased glutamate levels in prefrontal cortex (Hermann et al., 2012) and basal ganglia (Zahr et al., 2009
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