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Normally, this GSSG is recycled by reductases to maintain sufficient intracellular levels of reduced GSH
To monitor cell death and morphology, cells were visualized using the inverted microscope (Leica, DMi1, Germany)
This is especially true for glutathione
Factors that contribute to its development include: Hormonal fluctuations (pregnancy, birth control pills, hormone therapy) Genetic predisposition UV exposure and photoaging Emotional stress Sleep disturbances Photosensitizing medications Chronic inflammation What makes melasma particularly frustrating is its multifaceted nature
