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Intra-articular injection studies in rabbit osteoarthritis models have since explored AOD-9604 in combination with hyaluronic acid for cartilage repair

10.1016/j.semcdb.2019.11.013 82 FiondaC.StabileH.CerboniC.SorianiA.GismondiA.CippitelliM.et al (2020)

As noted earlier, several aminotransferases have been shown to catalyze a -elimination reaction with TFEC (Table 1)