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Within seconds, neuronal adenosine triphosphate (ATP) depletion triggers a glycolytic surge flooding cells with lactate, destabilizing pH, and paralyzing ion pumps, a biochemical crisis manifesting as cytotoxic edema and acute cognitive-motor dysfunction [16]
Nishida Y, Ayoub E, Scruggs D, Khazaei S, Munir F, Ostermann LB, Mak PY, Ke B, Carter BZ, Baran N, Maiti A, Mohanty V, Chen K, Navin N, Haferlach T, Ren Z, Tong Y, Chen D, Issa GC, Andreeff M
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Livingstone R, Boyle JG, Petrie JR
