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The changes in GSH that occur with CS are not well investigated

These protective actions were accompanied by a increase in the expression rate of B-cell lymphoma-2 (Bcl-2)/Bcl-2-associated X protein (Bax) and poly(ADP-ribose) polymerase cleavage by the inactivation of caspase-3

18 The American Academy of Otolaryngology recommends inner ear injection of steroids for patients who do not respond to conventional treatment

Future opportunities include hybrid nanoplatforms that integrate redox responsiveness with imaging and enhanced safety, as well as the use of patient-specific GSH/GSSG profiles to guide individualized therapy