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Dosis y formas de suplementacin recomendadas La dosis de suplemento de L-carnitina depende de su presentacin y propsito

2,15,18 Lactic acidosis is a manifestation of poor tissue perfusion and can be aggravated by inhibition of mitochondrial calcium entry leading to decreased pyruvate dehydrogenase activity.18,19 Other effects are bowel infarction and ileus.2,20-22 Pulmonary oedema23-26 (both cardiogenic and non-cardiogenic) might be caused by excessive fluid resuscitation and precapillary vasodilatation, resulting in increased transcapillary pressure

Hereditary or acquired defects in the transport mechanisms are the major cause of l-carnitine deficiency, leading to pathologies such as cardiomyopathy and skeletal muscle myopathy [12,13]