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PGC-1 attenuates inflammation through suppression of NF-B signaling and NLRP3 inflammasome activation, linking mitochondrial function to inflammatory control [126,127,128]

We demonstrate here that metabolism by intestinal microbiota of dietary l-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice

Cell Rep 23(3):796-807 2018 PMC5947873 Bhandari M, Mathur W, Kosta S, Mishra AK, Cummings DE

Additionally, daily, weekly, and monthly cramps completely resolved in 31.9%, 23.1%, and 14.3% of the patients, respectively
