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Alternatively, some type I TA systems are arranged with non-overlapping genes, but the transcripts show sufficient complementarity for duplex formation when encoded in trans

For instance, ethacrynic acid has been found to be predominantly metabolised by GSTP1, whereas transstilbene oxide is a specific substrate for GSTM1 (van Bladeren, 2000)

That is why glutathione for dark spots may be the best way to get that confidence boost

Trends Pharmacol
