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Description
In rodent models, Sema has been shown to activate GLP-1 receptors in the hypothalamus, indirectly affecting TSH (thyroid-stimulating hormone) levels and downstream thyroid hormone regulation

The topical foam (Extina) was associated with an increased incidence of contact sensitization, including photosensitivity in dermal safety studies

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Cortex 29 , 11211138 (2019)
