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For patients without neurological involvement, the initial regimen is typically 1 mg intramuscularly three times weekly for 2 weeks
A 2014 trial tested 4 grams per day of IV L-carnitine for 12 weeks in patients with metabolic syndrome and found improvements in body weight, cholesterol levels, insulin sensitivity, and inflammation markers
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Criteria for necrosis included karyorrhexis (loss of nucleus) and/or degeneration of cytoplasm with either coagulative or liquefactive changes
