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For nociceptive pain, treatment progresses from foundational analgesics (e.g., NSAIDs, paracetamol) to interventional procedures, emphasizing the mitigation of tissue injury and inflammation
Conventional chemotherapy: millions of cures, unresolved therapeutic index
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These findings underscore the pivotal role of JAB1 in regulating breast cancer progression and indicate that JAB1 inhibitors could serve as promising therapeutics for patients with elevated CUL4B expression
