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Bumetanide for the treatment of seizures in newborn babies with hypoxic ischaemic encephalopathy (NEMO): an open-label, dose finding, and feasibility Phase 1/2 trial

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Adv Neurobiol 13:133171 Martn-Rufin M, Nascimento-Gomes R, Higuero A et al (2014) Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells

The first and rate-limiting step of GSH synthesis is catalyzed by glutamate-cysteine ligase, which is regulated by cysteine availability at the level of transcription and translation 6